HPTN 052 and the future of HIV treatment and prevention
نویسندگان
چکیده
منابع مشابه
Association of HIV diversity and virologic outcomes in early antiretroviral treatment: HPTN 052
Higher HIV diversity has been associated with virologic outcomes in children on antiretroviral treatment (ART). We examined the association of HIV diversity with virologic outcomes in adults from the HPTN 052 trial who initiated ART at CD4 cell counts of 350-550 cells/mm3. A high resolution melting (HRM) assay was used to analyze baseline (pre-treatment) HIV diversity in six regions in the HIV ...
متن کاملHIV-1 Transmission during Early Antiretroviral Therapy: Evaluation of Two HIV-1 Transmission Events in the HPTN 052 Prevention Study
In the HPTN 052 study, transmission between HIV-discordant couples was reduced by 96% when the HIV-infected partner received suppressive antiretroviral therapy (ART). We examined two transmission events where the newly infected partner was diagnosed after the HIV-infected partner (index) initiated therapy. We evaluated the sequence complexity of the viral populations and antibody reactivity in ...
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ژورنال
عنوان ژورنال: The Lancet
سال: 2011
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(11)61117-3